There was no biological evidence of a process of programmed aging, so the theory remained as just an academic possibility. There were still plenty of women midwives and herbalists, but they were rarely part of the Church-dominated healing profession. Advances in chemotherapy have resulted in improvements in disease-free survival and overall survival for persons with cancer, and these improved outcomes are often associated the use of taxane-based regimens Jones et al. This applies to food substances such as olive oil and walnuts as well to many of the firewall supplements such as curcumin and resveratrol. As the hormones run down, so do all of the body systems which they regulate.
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Men may develop an enlargement of breast tissue, known as gynecomastia, testicular atrophy, and a reduced sperm count. Compounds with a high ratio of androgenic to an anabolic effects are the drug of choice in androgen-replacement therapy e. This disassociation is less marked in humans, where all AAS have significant androgenic effects. A commonly used protocol for determining the androgenic: The VP weight is an indicator of the androgenic effect, while the LA weight is an indicator of the anabolic effect.
Two or more batches of rats are castrated and given no treatment and respectively some AAS of interest. Animal studies also found that fat mass was reduced, but most studies in humans failed to elucidate significant fat mass decrements.
The effects on lean body mass have been shown to be dose-dependent. Both muscle hypertrophy and the formation of new muscle fibers have been observed. The hydration of lean mass remains unaffected by AAS use, although small increments of blood volume cannot be ruled out.
The upper region of the body thorax, neck, shoulders, and upper arm seems to be more susceptible for AAS than other body regions because of predominance of ARs in the upper body. After drug withdrawal, the effects fade away slowly, but may persist for more than 6—12 weeks after cessation of AAS use.
Overall, the exercise where the most significant improvements were observed is the bench press. The measurement of the dissociation between anabolic and androgenic effects among AAS is based largely on a simple although arguably unsophisticated and outdated model involving rat tissue bioassays. The intracellular metabolism theory explains how and why remarkable dissociation between anabolic and androgenic effects can occur despite the fact that these effects are mediated through the same signaling receptor, and of course why dissociation is invariably incomplete.
An animal study found that two different kinds of androgen response elements could differentially respond to testosterone and DHT upon activation of the AR. Changes in endogenous testosterone levels may also contribute to differences in myotrophic—androgenic ratio between testosterone and synthetic AAS. Testosterone can be metabolized by aromatase into estradiol , and many other AAS can be metabolized into their corresponding estrogenic metabolites as well.
The major effect of estrogenicity is gynecomastia woman-like breasts. AAS are androstane or estrane steroids. As well as others such as 1-dehydrogenation e. The most commonly employed human physiological specimen for detecting AAS usage is urine, although both blood and hair have been investigated for this purpose. The AAS, whether of endogenous or exogenous origin, are subject to extensive hepatic biotransformation by a variety of enzymatic pathways.
The primary urinary metabolites may be detectable for up to 30 days after the last use, depending on the specific agent, dose and route of administration. A number of the drugs have common metabolic pathways, and their excretion profiles may overlap those of the endogenous steroids, making interpretation of testing results a very significant challenge to the analytical chemist.
Methods for detection of the substances or their excretion products in urine specimens usually involve gas chromatography—mass spectrometry or liquid chromatography-mass spectrometry.
The use of gonadal steroids pre-dates their identification and isolation. Medical use of testicle extract began in the late 19th century while its effects on strength were still being studied. In the s, it was already known that the testes contain a more powerful androgen than androstenone , and three groups of scientists, funded by competing pharmaceutical companies in the Netherlands, Germany, and Switzerland, raced to isolate it.
The chemical synthesis of testosterone was achieved in August that year, when Butenandt and G. Wettstein, announced a patent application in a paper "On the Artificial Preparation of the Testicular Hormone Testosterone Androstenoneol. Clinical trials on humans, involving either oral doses of methyltestosterone or injections of testosterone propionate , began as early as Kennedy was administered steroids both before and during his presidency.
The development of muscle-building properties of testosterone was pursued in the s, in the Soviet Union and in Eastern Bloc countries such as East Germany, where steroid programs were used to enhance the performance of Olympic and other amateur weight lifters. In response to the success of Russian weightlifters, the U.
The new steroid was approved for use in the U. It was most commonly administered to burn victims and the elderly. The drug's off-label users were mostly bodybuilders and weight lifters.
Although Ziegler prescribed only small doses to athletes, he soon discovered that those having abused Dianabol suffered from enlarged prostates and atrophied testes. Three major ideas governed modifications of testosterone into a multitude of AAS: Androgens were discovered in the s and were characterized as having effects described as androgenic i. Although anabolic steroid was originally intended to specifically describe testosterone-derived steroids with a marked dissociation of anabolic and androgenic effect, it is applied today indiscriminately to all steroids with AR agonism-based anabolic effects regardless of their androgenic potency, including even non-synthetic steroids like testosterone itself.
The legal status of AAS varies from country to country: Unlawful distribution or possession with intent to distribute AAS as a first offense is punished by up to ten years in prison. Those guilty of buying or selling AAS in Canada can be imprisoned for up to 18 months. In Canada, researchers have concluded that steroid use among student athletes is extremely widespread. A study conducted in by the Canadian Centre for Drug-Free Sport found that nearly 83, Canadians between the ages of 11 and 18 use steroids.
AAS are readily available without a prescription in some countries such as Mexico and Thailand. The history of the U. The same act also introduced more stringent controls with higher criminal penalties for offenses involving the illegal distribution of AAS and human growth hormone. By the early s, after AAS were scheduled in the U. In the Controlled Substances Act, AAS are defined to be any drug or hormonal substance chemically and pharmacologically related to testosterone other than estrogens , progestins , and corticosteroids that promote muscle growth.
The act was amended by the Anabolic Steroid Control Act of , which added prohormones to the list of controlled substances , with effect from January 20, In the United Kingdom, AAS are classified as class C drugs for their illegal abuse potential, which puts them in the same class as benzodiazepines.
Part 1 drugs are subject to full import and export controls with possession being an offence without an appropriate prescription. There is no restriction on the possession when it is part of a medicinal product.
Part 2 drugs require a Home Office licence for importation and export unless the substance is in the form of a medicinal product and is for self-administration by a person. Many other countries have similar legislation prohibiting AAS in sports including Denmark,  France,  the Netherlands  and Sweden. United States federal law enforcement officials have expressed concern about AAS use by police officers.
It's not that we set out to target cops, but when we're in the middle of an active investigation into steroids, there have been quite a few cases that have led back to police officers," says Lawrence Payne, a spokesman for the United States Drug Enforcement Administration.
Following the murder-suicide of Chris Benoit in , the Oversight and Government Reform Committee investigated steroid usage in the wrestling industry. The documents stated that 75 wrestlers—roughly 40 percent—had tested positive for drug use since , most commonly for steroids. AAS are frequently produced in pharmaceutical laboratories, but, in nations where stricter laws are present, they are also produced in small home-made underground laboratories, usually from raw substances imported from abroad.
As with most significant smuggling operations, organized crime is involved. In the late s, the worldwide trade in illicit AAS increased significantly, and authorities announced record captures on three continents. In , Finnish authorities announced a record seizure of A year later, the DEA seized In the first three months of , Australian customs reported a record seizures of AAS shipments.
Illegal AAS are sometimes sold at gyms and competitions, and through the mail, but may also be obtained through pharmacists, veterinarians, and physicians. AAS, alone and in combination with progestogens , have been studied as potential male hormonal contraceptives. From Wikipedia, the free encyclopedia. This article is about androgens as medications.
For androgens as natural hormones, see Androgen. Ergogenic use of anabolic steroids. Use of performance-enhancing drugs in sport.
Illegal trade in anabolic steroids. Pharmacy and Pharmacology portal. British Journal of Pharmacology. Houglum J, Harrelson GL, eds. Principles of Pharmacology for Athletic Trainers 2nd ed. Int J Sports Med. Mini Rev Med Chem. Anabolic-androgenic steroid therapy in the treatment of chronic diseases". Clinics in Endocrinology and Metabolism. Pharmacology Application in Athletic Training. Clinical Guidelines for Prevention and Treatment. Royal College of Physicians. Anabolic Steroids and the Athlete, 2d ed.
Food and Drug Administration. Retrieved 21 June A systematic review and meta-analysis". Expert Opinion on Pharmacotherapy. Current Allergy and Asthma Reports.
Clinics in Liver Disease. The named reference Llewellyn was invoked but never defined see the help page. Neidle 19 March Pharmacology and Therapeutics for Dentistry - E-Book. The Environmental Medicine Series Chemical compounds ubiquitous in our food, air, and water are now found in every person's body. The bioaccumulation of these compounds can lead to a variety of metabolic and systemic dysfunctions, and in some cases outright disease states.
The bioaccumulation of these compounds in some individuals can lead to a variety of metabolic and systemic dysfunctions, and in some cases outright disease states. The systems most affected by these xenobiotic compounds include the immune, neurological, and endocrine systems.
These compounds are used in a variety of settings, are ubiquitous, and off-gas readily into the atmosphere. Asa result of their overuse, they can be found in detectable level virtually all samples of both indoor and outdoor air.
Certain of these compounds are detectable in adipose samples of all U. Once introduced to the body through food or vapor, mercury is rapidly absorbed and accumulates in several tissues, leading to increased oxidative damage, mitochondrial dysfunction, and cell death. Mercury primarily affects neurological tissue, resulting in numerous neurological symptoms, and also affects the kidneys and the immune system. Many pests are now pesticide resistant due to the ubiquitous presence of pesticides in our environment.
Chlorinated pesticide residues are present in the air, soil, and water, with a concomitant presence in humans. Potentially beneficial dietary interventions include identifying and treating blood glucose dysregulation, identifying and avoiding allergenic foods, and avoiding suspected triggering agents such as alcohol, aspartame, and monosodium glutamate. Nutrients that may reduce seizure frequency include vitamin B6, magnesium, vitamin E, manganese, taurine, dimethylglycine, and omega-3 fatty acids.
Supplementation with folic acid, vitamin B6, biotin, vitamin D, and L-carnitine may be needed to prevent or treat deficiencies resulting from the use of anticonvulsant drugs. However, arginine, yohimbine, Panax ginseng, Maca, and Ginkgo biloba all have some degree of evidence they may be helpful for erectile dysfunction.
This interest is also bringing to light some of the oldest natural remedies for both sexual dysfunction and enhancement. Traditional Chinese herbalists treat sexual imbalances such as impotence or reduced desire by improving adrenal energy, muscle strength and endurance with herbs that increase vitality and immunity. For improved sexuality, herbal adrenal tonics are often combined with moistening or blood-building herbs that reduce stress and increase sexual fluids.
Harmonizing sexual drive and capacity with sexual fluids is said to bring happiness, compassion and love. Not all women with the virus develop cervical dysplasia or cervical cancer. It has been postulated there are multiple host factors that contribute to progression of disease.
Many of these factors, such as nutrient deficiencies, can be reversed, which will result in regression of dysplastic lesions. Studies have shown dietary intervention and nutrient supplementation to be effective in preventing cervical cancer.
Soy and other phytoestrogens, black cohosh, evening primrose oil, vitamin E, the bioflavonoid hesperidin with vitamin C, ferulic acid, acupuncture treatment, and regular aerobic exercise have been shown effective in treating hot flashes in menopausal women. To know the cause is to know the cure. The cause of PMS appears to be a complicated interplay among hormones, neurotransmitters, nutrients and psychosocial factors.
To complicate the picture further, the same imbalances are not present in every person suffering from PMS. This article is a review of the literature, citing numerous studies, sometimes with conflicting views, of the etiology and non-drug treatment for premenstrual syndrome. Specific nutrients and botanicals are discussed as they relate to particular neuroendocrine imbalances. In view of the fact that there appears not to be one particular deficiency or excess which can be identified in each case of PMS, the most reliable method of treatment involves a comprehensive approach which includes dietary changes, supplementation of specific nutrients and botanicals, and when indicated, use of identical to natural hormones such as progesterone.
Refer to the Women's Health Page for more information on this topic. Refer to the Chiropractic and Female Issues Page for more information. Evidence from multiple sources support the concept of decreased flux through the serotonin pathway in fibromyalgia patients. The reduced sensitivity to pain and improvement in quality of life measured in this study appear to be clinically relevant and a larger, double-blind study is warranted.
Individuals with gallstones may experience various gastrointestinal symptoms and are also at risk of developing acute or chronic cholecystitis. Nutritional supplements that might help prevent gallstones include vitamin C, soy lecithin, and iron.
While minimal scientific evidence supports the efficacy of this treatment, anecdotal reports suggest the gallbladder flush may be beneficial for some people. Bromelain also appears to have effects on cell surface antigens.
Although all of its mechanisms of action are still not completely resolved, it has been demonstrated to be a safe and effective supplement. A great deal of this information has addressed cholesterol and fat intake saturated vs. In addition to these studies, a number of scientists have been investigating the connection between micro-nutrients vitamins, minerals, amino acids, flavonoids, coenzymes and heart disease.
The oxidation of LDL cholesterol has been linked to vascular damage leading to atherosclerotic plaques. Antioxidant activity and subsequent inhibition of LDL oxidation has been attributed to the dietary and supplemental intake of specific micro-nutrients, including vitamin E, vitamin C, vitamin B6, glutathione, flavonoids, beta carotene, lipoic acid, and coenzyme Q In addition, elevated homocysteine levels have been implicated in a number of other clinical conditions, including neural tube defects, spontaneous abortion, placental abruption, low birth weight, renal failure, rheumatoid arthritis, alcoholism, osteoporosis, neuropsychiatric disorders, non-insulin-dependent diabetes, and complications of diabetes.
Nutritional intervention with the cofactors required for optimal metabolism of the methionine-homocysteine pathways offers a new, integrated possibility for primary prevention and treatment. Supplementation with betaine, vitamin B12, folic acid, and vitamin B6 assists in optimizing methyl- and sulfur-group metabolism, and might play a significant role in the prevention and treatment of a wide array of clinical conditions.
Deficiencies of CoQ10 have been documented in patients with heart disease. Administration of CoQ10 has been shown to prolong survival and improve quality of life in patients with cardiomyopathy. In patients with congestive heart failure, CoQ10 ameliorated symptoms, reduced the number of hospitalizations and appeared to increase the survival rate. Treatment with CoQ10 may also reduce the number of anginal attacks in patients with stable angina pectoris.
CoQ10 has been shown to prevent adriamycin cardiotoxicity and to reduce the incidence of postoperative cardiac dysfunction in patients undergoing heart surgery.
Several studies indicate that CoQ10 may also have a role in the treatment of essential hypertension. This nutrient may be of value for patients with diabetes mellitus or male infertility, but additional studies are needed in these areas. CoQ10 status may be adversely affected by treatment with certain cholesterol-lowering drugs, beta blockers, tricyclic antidepressants, and phenothiazines.
C-reactive Protein and the Inflammatory Disease Paradigm: This may account for alpha-tocopherol's positive effect on cardiovascular morbidity and mortality. Finally, polyphenolic compounds present in virgin olive oil also have anti-inflammatory and antioxidative effects in cardiovascular disease. The phenolic compounds in virgin olive oil may explain some of the protective effects found in epidemiological studies.
Vitamin E supplementation may also be beneficial in the prevention of cerebro- and peripheral vascular diseases. Refer to the Vitamin E Page for more information on this topic. Refer to the Resveratrol Page for more information.
The loss of vascular integrity is associated with the pathogenesis of both hemorrhoids and varicose veins. Several botanical extracts have been shown to improve microcirculation, capillary flow, and vascular tone, and to strengthen the connective tissue of the perivascular amorphous substrate. Oral supplementation with Aesculus hippocastanum, Ruscus aculeatus, Centella asiatica, Hamamelis virginiana, and bioflavonoids may prevent time-consuming, painful, and expensive complications of varicose veins and hemorrhoids.
The use of the botanical components glycyrrhizin, catechin, silymarin and phytosterols, and the antioxidants N-acetylcysteine and vitamin E are reviewed for their efficacy in treating chronic hepatitis and affecting liver damage.
Therefore, the search for other treatments is of utmost importance. Several natural products and their derivatives have demonstrated benefit in the treatment of hepatitis C and other chronic liver conditions. Other herbal and nutritional supplements have mechanisms of action that make them likely to be of benefit. Although billions of dollars are spent annually in the United States for the treatment and detection of cardiovascular disease, current conventional treatments have done little to reduce the number of patients with hypertension.
Alternative medicine offers an effective way to decrease the rising number of people with high blood pressure. Research has found a variety of alternative therapies to be successful in reducing high blood pressure including diet, exercise, stress management, supplements, and herbs. Refer to the Chiropractic and Blood Pressure Page for more on this topic.
This phytosterol complex seems to target specific T-helper lymphocytes, the Th1 and Th2 cells, helping normalize their functioning and resulting in improved T-lymphocyte and natural killer cell activity. A dampening effect on overactive antibody responses has also been seen, as well as normalization of the DHEA: A large portion of antibiotics are dispensed by pediatricians treating common outpatient infectious diseases.
The overuse of antimicrobials is beginning to be discouraged as scientific evidence is emerging to support the use of other therapies. In pediatric practice an emphasis on accurate diagnoses, control of environmental risk factors, and utilization of complementary and alternative medicine CAM therapies could reduce antibiotic prescribing. The immune-enhancing properties also suggest an array of clinical uses, both in preventive medicine, due to its ability to build a more responsive immune system, and in clinical medicine, as a therapeutic agent in conditions associated with lowered immune function, decreased NK activity, or chronic viral infection.
Immunological Activity of Larch Arabinogalactan and Echinacea: Food and Drug Administration FDA as a source of dietary fiber, but also has potential therapeutic benefits as an immune stimulating agent and cancer protocol adjunct. Refer to the Immunity and Nutrition Page for more information on this topic. Refer to the Chiropractic and Immune FunctionPage for more information.
A number of nutritional therapies have been shown to improve sperm counts and sperm motility, including carnitine, arginine, zinc, selenium, and vitamin B Numerous antioxidants have also proven beneficial in treating male infertility, such as vitamin C, vitamin E, glutathione, and coenzyme Q Refer to the Chiropractic and Infertility Page for more information on this topic.
Bacillus coagulans is a notable exception which, due to its sporulated form, survives without special handling and proliferates in the gastrointestinal environment. The difficulty of differential diagnosis and its treatment may significantly delay initiation of optimal therapy. In addition, most common pharmacological approaches target IBS symptom management rather than treatment, and prescribed medications often result in significant side effects.
The purposes of this review article are to: The Causes of Intestinal Dysbiosis: Irritable bowel syndrome, inflammatory bowel disease, rheumatoid arthritis, and ankylosing spondylitis have all been linked to alterations in the intestinal microflora.
The intestinal dysbiosis hypothesis suggests a number of factors associated with modern Western living have a detrimental impact on the microflora of the gastrointestinal tract. Factors such as antibiotics, psychological and physical stress, and certain dietary components have been found to contribute to intestinal dysbiosis.
Inflammatory Bowel Disease Series. Therefore, herbal and other natural sleep aids are gaining popularity, as herbs commonly used for their sedative-hypnotic effects do not have the drawbacks of conventional drugs. Whether alternative therapies possess activity similar to conventional therapies needs further evaluation. The syndrome presents differently in many individuals, with the unifying factor being chronic pelvic pain and disruption of daily life activities.
Many etiologies have been proposed as causative factors for IC, although it is likely triggered by more than one process. Treatment for many individuals revolves around symptom management and improving quality of life; however, it is imperative to remove aggravating factors such as food and daily stressors. Treatment will vary for individuals, as symptoms and etiology will differ. This article discusses nutritional and other non-toxic approaches to treating IC. Basic scientific research has uncovered the mechanisms by which some plants afford their therapeutic effects.
Silybum marianum milk thistle has been shown to have clinical applications in the treatment of toxic hepatitis, fatty liver, cirrhosis, ischemic injury, radiation toxicity, and viral hepatitis via its antioxidative, anti-lipid peroxidative, antifibrotic, anti-inflammatory, immunomodulating, and liver regenerating effects.
Clinical research in this century has confirmed the efficacy of several plants in the treatment of liver disease, while basic scientific research has uncovered the mechanisms by which some plants provide their therapeutic effects. This article is Part Two in a review of botanicals used in the treatment of liver disease.
Curcuma longa turmeric , Camellia sinensis green tea , and Glycyrrhiza glabra licorice are reviewed in this installment. Silybum marianum milk thistle and Picrorhiza kurroa kutkin were reviewed in Part One.
Nonalcoholic Fatty Liver Disease: Relationship to Insulin Sensitivity and Oxidative Stress. There is increasing evidence that steatosis in NASH is a result of the pathology in fat metabolism occurring in obesity and insulin resistance.
Yes, you are required by law to submit to his or her advice and cooperate in doing the recommendations he or she makes. Yes, your only chance of survival in your battle in this war is to work with your physician. Yes, but there are many things that are helpful in your fight that your physician cannot do for you. In dealing with your metabolism, you must do it yourself. This book is to help guide you through the things you can do to help yourself and accomplish the best possible state of health.
Yes, work with your physician and do all he or she advises, and study and glean all you can from this booklet. My fellow researcher, Dr. We reviewed thousands of medical records of Cancer patients. We spent hundreds of hours in Medical School Libraries. We spent thousands of hours in University Law Libraries. We brought many legal cases in the State and Federal Courts of Pennsylvania.
We appealed to the 3rd Circuit of the Federal Courts several times and appealed to the U. Supreme Court 5 times. During this time Dr. Morrison and I collected more than adequate data and endured sufficient experiences to honestly and with Christian love for our fellow Cancer patients, and without rancor, make the following statements. To put it candidly, we know whereof we speak and write. See below and take note in Chapter X.
Kelley is a dentist. Morrison was of a different mind. I know our opinions about the Medical Establishment are repulsive and unbelievable to the honest, God fearing, Christian citizen. Nevertheless, they are true and we have encountered so many such experiences we must bring to your attention at least one of these horrible stories.
Morrison got an urgent call from her little brother, David. He had a small lump, about the size of a pea, on the left side of his neck, just above the collarbone.
His doctor in New Jersey, knowing the stress David was under with his "wife to be" told him to just calm down and get his family situation resolved and watch it and check again in six months. Carol knew from her medical training that if the lump was malignant it was only a metastasis of a tumor mass, usually found in the chest between the lungs. She asked me to ask the Holy Spirit for confirmation. To verify the Holy Spirit, Carol did a "scan" in the hospital where she was working.
It was agreed to wait six months and then check David again. She demanded the nodule be removed and biopsied to prove it was cancer. If she demanded a diagnosis of cancer and could pay for it, "she will get it. Anderson Cancer Center in Houston; if you are rich enough and live in the central U. Everyone gets a piece of the pie! The advice of the New York doctors was: We do see a swelling in the nasal sinus.
It would be closer to home for David to be treated in Philadelphia and less stress. Back in Philadelphia, mother demanded a biopsy of the nasal sinus; the fact that David had allergies was never considered. The surgery was a disaster; the surgeon ruptured a major artery and nearly killed David. No biopsy of a life or death situation was encountered. All manor of chemotherapy and radiation was then started. In Pittsburgh David was scalped; his skull was sawed from ear to ear and set aside.
Seventeen biopsy samples were taken, digging as close to the brain as possible. David was going to five doctors and each one was giving him something different and not knowing or caring what the others were treating him with. All this was accomplished and treatment performed when there was no positive biopsy ever reported.
All they could say was: Morrison and I were devastated. We constantly asked God why such devastating and cruel experiences were necessary when David did not even have cancer! Maybe it was for you, the readers of this booklet — for your education and understanding. Carol and I had seen enough, long before David.
Cancer is basically a deficiency disease — a deficiency of the pancreatic enzymes. This is a deficiency of the free active enzymes in the tissues of the body. Since and the passage of the Hatch Act, individuals and physicians may legally support human metabolism by diet, nutritional supplements and certain procedures as long as they are not harmful.
In fact, for many years it has been accepted that one must add vitamins, minerals, trace minerals, amino acids, etc. The modern diet is quite deficient in certain foods that have in the past been mainstays of good nutrition and the support of health. The most outstanding missing group as a whole is the organ meats, such as kidney, liver, stomach, intestinal tract tripe, and lung. To get these today one must obtain them in the form of nutritional supplements.
Pancreas tissue or sweetbreads without a doubt, indicated by our 30 odd years of research, is the most deficient item in our food chain. It should be noted that the pancreas is the most needed of all the missing organ meats from our diets. It must be supplied in our diets or serious deficiencies result. Low temperature processed pancreas gland enzymes are available to the public in various Metabolic Formulas listed below.
These nutritional products are designed to support the normal metabolic processes of human metabolism. Below are the Metabolic Formulas Dr. They have been helpful to thousands of his metabolic counselees. For the amount to take and the timing see below. Formula E — For those who have difficulty swallowing, this enteric-coated caplet has proven to be helpful. Formula E also contains enzyme activators that are lacking in some cancer patients. Activators are also normally secreted in the first six inches of the small intestine as soon as food from the stomach and enzymes from the pancreas arrive.
If the pancreas contained this activator the pancreas would digest itself. A lack of these activators prevents the pancreatic enzymes from digesting food or destroying cancer cells in the body. Formula H — For those who have Hay Fever or other allergies — 6 caplets should be taken with each meal.
Formula L — For those who have been diagnosed by their physician as having Leukemia. Formula P — For those who choose to invest in Prevention — 2 or 3 caplets should be taken with each meal and at bedtime. This is for pancreas support, not for pancreas failure. Formula T — Pancreas Self-Test — 6 caplets with each meal and at bedtime.
Formula W — For Weight Control — 2 to 6 caplets should be taken with each meal. It is far more important than one can possibly realize to take the Metabolic Formulas at the proper time. The most essential part of resolving the metabolic malfunction of those with pancreatic failure is to get the enzymes to the affiliated areas of deterioration.
We must have enough enzymes there to stop any further deterioration of body tissue. Some have found it easier if one starts the first week by taking 6 caplets each at the 6 suggested intake times; then 9, then up to the suggested The raw materials for the repair and rebuilding of the body must be cycled. Taking the Metabolic Formulas during the "On" cycle provides a saturation of needed nutrients.
Stopping the Metabolic Formulas during the "Off" cycle provides the necessary time for the body to repair, rebuild and detoxify. Take the Metabolic Formulas for 10 or more days, until one becomes toxic, but no longer than 25 days. It is best to stay On your Metabolic Formulas for 10 to 25 days. However, when you suffer negative symptoms anytime after the third day you may Stop taking them at that point. Remain Off the Metabolic Formulas for 5 days. You must give the body time to detoxify.
Stay Off the Metabolic Formulas the full 5 days even if you feel well enough to continue. Give your body time for repair and rebuilding. You must continue your detoxification program during the "Off" cycle. If you feel worse while you are Off the Metabolic Formulas you should go back On them immediately and try to go Off them again in 25 days or if you feel toxic.
Essential Fatty Acids are critical nutrients, not produced within the body, and must be supplied through the diet. These Fatty Acids are needed for the function of the immune system as well as cardiovascular and brain metabolism. This special formula is very high in Omega 3 and restores needed balance of Cholesterol and Triglycerides.
Balance usually occurs in 6 to 8 months by taking 1 tablespoon two times each day. This formula is very high in Omega 3 and Omega 6 and restores and maintains the balance of cholesterol and triglycerides. Taking one tablespoon each day has been adequate and helpful to many. The cardiovascular system is of the utmost importance. It would be counter-productive indeed to survive cancer only to be wiped out with malfunction of the cardiovascular system.
HRT is a solution of ortho-phosphoric acid. Suggested daily intake is 45 to 90 drops daily taken in juice, hot or cold tea, carbonated beverage or water.
Multiple Mineral, 1 per day optional — there are sufficient minerals in the above enzyme Formulas. Multiple Vitamin, 1 per day optional — there are sufficient minerals in the above enzyme Formulas. Kelley does not deny that his approach applies extreme measures. He maintains that extreme measures are required when you have allowed your health to fall so low that your have left yourself vulnerable to cancer.
He has identified four major lines of defense against cancer: All of them depend heavily on nutrition for their strength. You take so many pills in order to be sure that your glands will be totally supported, your immune system highly stimulated, and your body chemistry properly balanced. In reality, a person very rarely dies of cancer. It is always starvation and toxicity. As the malignant tumor grows it gives off waste products, which must be eliminated through the colon, liver, kidneys, lungs and skin.
These waste products accumulate and gradually overburden the body. Most persons then die of toxemia. Before any disease can be cured, the waste products and impurities must be cleansed from the body. The sooner this is done, the sooner the body can begin repairing itself. Kelley recommends that you begin the detoxification process even before you have the nutritional supplements in your possession. It is absolutely imperative that the patient carefully follows the detoxification process after the supplements begin stimulating the release of wastes and debris.
Scientists have calculated that a person has between 70 and trillion cells in his or her body. This means we have over 70 trillion "garbage cans" needing to be emptied. In our culture we have not made allowances for, nor taught ourselves, the proper techniques of emptying these waste receptacles. It is no wonder that the people of our nation are so sick! Proper and thorough detoxification is just as important as good nutrition for anyone who has lived in the mainstream of a modern technological civilization for 10 or more years, and especially for anyone who has developed symptoms of a chronic degenerative disease.
The intensive program of concentrated nutrients outlined in this book will begin to make nutritional factors available to the cells, which they may not have had for many years. Consequently, cellular metabolism will speed up and an increased amount of metabolic waste will be dumped into the bloodstream. If it accumulates in the bloodstream, one will not feel well and the cells will not be able to utilize the fresh nutrients being provided by the nutritional program. When one eats food, it is digested in the mouth, stomach, and intestinal tract.
In the intestinal tract, the digested food is absorbed into the bloodstream, which takes it close to each individual cell. The food, along with oxygen, is transferred into the cell. In the cell, nutrients are metabolized into energy, carbon dioxide, water, and waste products of metabolism. It is the accumulation of these wastes, which frequently interferes with normal functions of the cells.
Principle factors necessary for a pure bloodstream are pure air, pure water, pure food, and the presence of oxygen brought in by exercise appropriate to your cardiovascular capacity. As the cells produce metabolic debris, the blood carries it to the organs of detoxification.
These organs are the liver, kidneys, lungs, skin, many of the mucous membranes, and the colon. If these organs of detoxification are themselves filled with debris, they of course cannot accept any more toxins. In such a case, the blood cannot accept further debris from the cells and, before long, there are 70 to trillion garbage cans completely full.
It is like the city dump being filled to capacity and not accepting any more garbage trucks. Before long, the entire community has become bogged down. The liver is the major organ of detoxification, and also the most stressed by our modern lifestyle.
One cannot live long without the heart, brain, kidneys, or pancreas, yet it is proper liver function, which prevents these organs from becoming diseased. Here, in addition to metabolic wastes, is where environmental contamination, food additives, and all other chemical pollutants are removed from the body.
You should be just as much or more concerned about the condition of your liver as about the condition of your heart. If you have had hepatitis, cirrhosis of the liver, infectious mononucleosis, or other liver damage, you should become very protective of this vital organ. The intake of anything that places undue stress on the liver should be eliminated entirely.
Such a list would include: Unrefined oils, or butter for sautéing, can be used without creating peroxides and free radicals, which are toxic to the liver.
Metabolizing essential fats cholesterol, triglycerides, lipoproteins and thus preventing their accumulation in the bloodstream where they often form deposits on blood vessel walls atherosclerosis. Secreting a fluid bile which stores in the gall bladder or the enlarged bile duct and empties into the small intestine. The bile acts as a carrier for all liver wastes. It is also essential for the proper digestion and assimilation of fats and all fat-soluble nutrients such as vitamins A, D, E, K, lecithin, and essential fatty acids.
The gall bladder is a hollow muscular organ which stores and concentrates bile and is attached to the undersurface of the liver. When a meal is eaten, especially if it contains some fats or oils, the gall bladder is stimulated to contract and should freely expel its contents into the small intestine to emulsify fatty nutrients for proper absorption, and to allow poisonous wastes which the liver has removed from the body to be eliminated through the intestines.
Many people living in our society today, even those in their teens, fail to have free, unobstructed flow of bile from the liver and gall bladder in response to food entering the small intestine. Eating refined or processed foods, eating fresh food which is mineral deficient because it is grown on depleted or chemically treated soil, lack of regular vigorous exercise, stress, multiple distractions during meals, and many other unnatural aspects of our lifestyle have combined to alter the chemistry of bile so that formation of solid particles from bile components is a commonplace occurrence among Americans.
These solid particles remain in the gall bladder or the base of the liver for many years and become progressively harder, sometimes calcifying into "gallstones. When a significant number of solid bile particles accumulate, the free flow of the gallbladder is diminished, causing progressive stagnation and congestion of the liver. The body begins to suffer the effects of poor assimilation of fat-soluble nutrients, which may play a role in the development of eczema, psoriasis, dry skin, falling hair, tendonitis, night blindness, accumulation of calcium in tissues, and sometimes prostate enlargement in men.
Hemorrhoids due to blockage of the portal vein draining the liver are often the result of this congestion. The importance of cleansing the debris from the liver and gall bladder, thus keeping the bile free flowing, cannot be overemphasized.
This can be effectively accomplished by doing the Liver-Gall Bladder Flush a form of which at one time was widely used at the world famous Lahey Clinic in Boston, MA , which is necessary even if one has had their gall bladder removed.
The four basic active principles in this procedure are:. Apple juice high in malic acid or ortho-phosphoric acid, which acts as a solvent in the bile to weaken adhesions between solid globules. Epsom salt magnesium sulfate , taken by mouth and enema, which allows magnesium to be absorbed into the bloodstream, relaxing smooth muscles. Large solid particles which otherwise might create spasms are able to pass through a relaxed bile duct.
Olive oil, unrefined, which stimulates the gall bladder and bile duct to contract powerfully, thus expelling solid particles kept in storage for years. Coffee enemas, which consist of a coffee solution retained in the colon. They activate the liver to secrete its waste into the bile, enhancing bile flow and further relaxing the bile duct muscle.
The Liver-Gall Bladder Flush is one of the most important procedures for persons over 15 years of age. The steps in doing this are not difficult and are as follows:.
For 5 days prior to the "Flush," consume as much apple juice or cider as the appetite permits, in addition to regular meals. Nutritional supplements should also be taken during this time.
The first preference for juice would be freshly juiced organic apples, and secondly, apple juice or cider unsweetened and preferably organic if possible purchased either from the health food or grocery store. A person should be sure to read the labels carefully and obtain a juice that has no additives whatsoever. If one is a severe hypoglycemic, is diabetic, or has difficulty tolerating the juice or cider, he or she may take 20 drops of HRT Phosfood Liquid or Super Phos 30 with each meal 60 drops daily in RO filtered water or distilled water or some type of juice other than apple.
Due to the high acidity, it is wise that one brush his teeth or rinse out his mouth with Milk of Magnesia or baking soda solution after taking the ortho-phosphoric acid. At noon on the sixth day, one should eat a normal lunch and take the Metabolic Formulas scheduled for that time. Two hours after lunch, 1 or 2 tablespoons of Epsom salt magnesium sulfate dissolved in 1 to 3 ounces of warm mineral water, RO filtered water or distilled water should be taken. The taste may be objectionable to some.
If so, the mixture can be followed by a little citrus juice if desired freshly squeezed if possible. This should be retained for 15 minutes and expelled. The coffee should be made as strong as one can tolerate but no stronger than 6 tablespoons of ground coffee per quart of water.
Five hours after lunch take 1 tablespoon of Epsom salt, dissolved as the previous dose Step 3. Six or seven hours after lunch, one may fast if desired. However, it is preferable to have a fresh fruit salad, using as many fresh fruits in season as possible.
Use heavy, unpasteurized whipping cream as a dressing on the salad, whipped with a little raw unheated honey if desired. One can eat as much as desired of the whipped-cream-covered salad. If fresh fruit is unavailable, frozen berries such as strawberries, blueberries, boysenberries, blackberries, raspberries, etc.
These should also be covered with whipped cream and a large portion eaten. Take citrus fruit or juice after the cream and fruit meal, if desired. For hypoglycemics, the cream should balance the fruit. However, each hypoglycemic should adjust the amount of salad eaten to his individual tolerance.
At bedtime, there can be 1 of 3 choices Note: Olive oil stimulates the gall bladder and bile duct to contract powerfully, thus expelling solid particles kept in storage for years. All juice should be freshly squeezed if possible: Take 4 tablespoons of unrefined olive oil or 4 tablespoons of Formula F followed by 1 tablespoon of citrus juice every 30 minutes until 6 ounces of oil have been consumed. This choice is preferable for those who are unusually weak or who have had gall bladder problems in the past.
It has been found helpful to rinse the mouth with an alcohol base drink like Sherry to cut out the residue of the oil taste. If an alcohol base drink is unobtainable, try a natural carbonated drink, or club soda. Do not swallow the alcohol drink or the carbonated drink.
If one should vomit during the consumption of the oil and juice, the procedure should be continued until it is finished. It is not necessary to make up for the amount that was vomited. Immediately upon finishing the oil and juice or while taking it , one should go to bed and lie on the right side with the right knee drawn up toward the chin for 30 minutes before going to sleep. If there is a strong feeling of nausea the following morning, one should try to remain in bed until it subsides somewhat.
Vomiting should not be forced. Upon arising, one must take another strong coffee enema with Epsom salt in it or, 1 hour before breakfast, take 1 tablespoon of Epsom salt dissolved in 1 to 3 ounces of warm mineral water, RO filtered water or distilled water. If one continues to feel nauseous or very sore in the upper abdomen even after the enema, a light diet of sprouts, fruit raw or steamed , yogurt or kefir, and freshly extracted vegetable juices especially with beet greens in them should be resumed.
If one finds that the Metabolic Formulas cause discomfort immediately after the flush, they may be omitted for three days. Taking one hydrochloric acid tablet at bedtime will help reduce any nausea during the night.
If you have a tendency to get nauseated from the oil, take 2 tablespoons of Aloe Vera juice after your doses of oil and citrus juice. Placing a hot water bottle over the liver area under the right ribcage during the night also helps relieve nausea. One should not be frightened by the above references to nausea, vomiting, soreness of the abdomen, etc.
Many people complete this procedure with minimal discomfort, and nearly everyone feels much better after completing it. Flushing the liver and gall bladder in the manner described if the gall bladder is present stimulates and cleans these organs as no other process does.
Oftentimes, persons suffering for years from gallstones, lack of appetite, billiousness, backaches, nausea, and a host of other complaints will find gallstone-type objects in the stool the day following the flush. These objects are light to dark green in color, very irregular in shape, gelatinous in texture, and of sizes varying from "grape seed" size to "cherry" size.
If there seems to be a large number of these objects in the stool, the flush should be repeated in 2 weeks. The fast should last one or two days. We are now giving the body a rest and an opportunity to cleanse itself of much waste on the individual cell level.
Each day of the fast one quart of fresh carrot juice and one pint of celery juice should be taken, along with all the RO filtered or distilled water desired. It is best to dilute the fresh juice with equal parts RO filtered or distilled water.
It is important to remember that unless sufficient fluids are taken the poisons become concentrated and are not eliminated in the natural way. If there were only one kind of pill that would help everybody, the cancer patient or otherwise, it would be "Okra-Pepsin-E3" made by Standard Process, Inc. Certain foods, such as pasteurized milk and many cooked foods, cause the mucus buildup on the wall of the small intestine raw foods do not cause this mucus buildup.
The mucus coats the villi on the wall of the small intestine. The villi are like tiny fingers that stick out from the intestinal wall to absorb nutrients from the digested food, which is primarily liquid. The mucus on the villi blocks the absorption of nutrients from the food.
Sometimes the mucus gets so thick and tough it is almost like a plastic film. Almost no nutrition can get through to the body. He or she would be starving and therefore would want to eat more food including protein.
That would lead to more of the pancreatic enzymes being used to digest the protein even though it could not be properly absorbed. When all the pancreatic enzymes are used up, there are none left in the blood to destroy cancer cells.
The okra is a very sticky, gooey, vegetable material. It tends to stick the pepsin enzyme to the mucus on the intestinal wall long enough to digest some of the mucus. The E-3 is a powerful tissue repair factor.
It was originally developed for the patient with stomach ulcers or colitis. If the Okra-Pepsin-E3 capsules are taken for a few days to several weeks, one after each meal reduce the amount of capsules if diarrhea occurs , the mucus will gradually be digested. The blood can then receive more nutrients from the food, even if it is from a poor diet.
Then, once a year, take the Okra-Pepsin-E3 capsules again for a few days or a week to keep the mucus from building back up. The mucus blockage varies with different people.
Sometimes it blocks minerals and larger molecules only, while in other people it partially blocks all nutrients. While taking the Okra-Pepsin-E3 capsules people who have heavily mucus-coated intestines might find mucus coming out with their stool, convoluted like the intestines. Kelley has had people who have been taking the capsules call him to say that they think they have just passed their intestines and what should they do? One year-old patient called Dr. Kelley to report that the Okra-Pepsin-E3 capsules worked a miracle by relieving reoccurring pain that she had suffered with for years.
The pain would come and go apparently without cause and felt like bricks were pressing against her internal organs and lower back and at the same time her right side and leg would feel numb. On the morning of the eighth day, after taking one Okra-Pepsin-E3 capsule with each meal for a week, she spent 45 minutes sweating, straining and pushing to have a bowel movement, and when it finally came out she could hardly believe what she saw — long, intertwined black ropes or collapsed tubes of mucus filled the toilet!
After this bowel movement and the disappearance of her pain she realized that there must have been a connection to eating a large meal and the pain — food passing through the intestine would push the mucus-coated intestine onto nerves, which caused the pain and numbness. The Okra-Pepsin-E3 is indicated for both underweight and overweight people. In both cases nutrients are not being absorbed. Even if they are taking enzymes to digest the food they eat, they absorb only the smaller carbohydrate molecules while the larger protein molecules are blocked.
In underweight people the carbohydrates are used efficiently burned for energy, not turned into fat , but the person becomes thin as they lose muscle mass from lack of protein absorption. In overweight people the carbohydrates are not used efficiently they are turned into fat , and this causes the person to become overweight as they also lose muscle mass. A high, retention enema, using coffee, should be taken to aid in the elimination of toxic waste material from the body.
After 35 years, Dr. Kelley still takes his daily enema. The coffee enema, besides stimulating liver detoxification, also has beneficial effects in cleaning the colon. Coffee is an excellent solvent for encrusted waste accumulated along the walls of the colon. The caffeine also directly stimulates the peristaltic muscle to contract more powerfully and loosen such deposits, which are occasionally visible as hard, black material and "ropes" of mucus. Gradually, as the protein metabolism of the body improves, the muscle tone of the bowel becomes normal and thorough evacuation is possible without the aid of the enema.
Essentially, the coffee enemas help the liver perform a task for which it was not designed — that of elimination in 1 or 2 years the accumulated wastes from many years of living in ignorance of the laws of nature. At first, most people dislike enemas and have psychological barriers against them. Ignorance of the purpose and function of the enema, as well as misunderstanding of the proper procedure for taking it bring about this aversion.
I have observed, however, that the persons most opposed to enemas soon reverse their prejudices and become the most avid supporters of them! In many cases, the enema relieves distress and gives a sense of well being and cleanliness never before experienced.
The proper removal of toxins and debris from the colon is absolutely essential in all conditions of disease and ill health. Enemas using coffee in the afternoon or evening may interfere with sound sleep. If enemas are needed at these times, many patients prefer to use only warm pure water omitting the coffee. But it is better to take coffee at these times also, and a weaker solution to permit sleep would be better than not using coffee at all. Just before bedtime each day, make a pot of coffee 1 quart.
Unplug coffeepot and allow to cool to room temperature. It is best to arise early enough each morning to allow time to take the enema in a relaxed, unhurried state. The coffee must be regular, non-instant, non-decaffeinated coffee. Aluminum or Teflon should not be used at any time!
We have found the coffee that is unboiled or prepared via the "drip method" is preferable. Use 3 to 4 tablespoons of ground coffee to 1 quart of Filtered Reverse Osmosis RO or distilled water. Any water that enters into the body should be RO filtered or distilled water. Avoidance of city water supplies always chlorinated, which has been strongly linked to hardening of the arteries, and often fluoridated, which has been strongly linked to cancer and thyroid disease is most essential to removing stress from the kidneys.
Pure RO filtered water or distilled water should be used for cooking and drinking — and even for preparing enemas, since a significant portion of the enema water may be absorbed and filtered through the kidneys. Even if one has a well, it should not be assumed safe. Often toxic amounts of copper, cadmium, and lead are picked up from the plumbing even if the well is pure.
If one distills water from a city supply, one must remember that certain hydrocarbon contaminants have a lower boiling point than that of water. The distiller should have a valve to permit their escape as they gasify.
If not, they will concentrate in the distilled water and will need to be removed by filtering through activated charcoal.
An acceptable Distilled Water System: H 2 0 Only, Inc. Filters breed deadly bacteria. If your water supply is dirty a filter will get dirty in less than 30 days — A filter should be changed every 30 days even if your water supply is clean. If a coffee enema makes a person jittery, shaky, nervous, nauseated, or light-headed, the coffee solution is too strong.
The amount of coffee can be adjusted from 1 teaspoon to 4 tablespoons per quart of water as tolerance level permits. The high, retention coffee enema should consist of 1 quart of coffee, held for 15 minutes. Some people, children especially, can take and retain only a pint 2 cups of enema solution at a time. If this is the case, one must take 2 enemas each time, one right after the other, and hold each for 15 minutes as directed. Upon rising each morning plug in the coffeepot for a few seconds to bring coffee to body temperature; unplug and take the morning coffee enema.
Before the enema do some form of mild exercise if possible, such as walking briskly. If one is extremely debilitated and weak, this step will of course need to be omitted until strength returns. Attempt a normal bowel movement.
The enema is much more effective if the colon has been evacuated. In many cases, not enough bulk collects to instigate a normal bowel movement. When no normal bowel movements are forthcoming, the enema cleans the colon adequately. After the normal bowel movement, if one is forthcoming, or before taking the coffee retention enema, most people find that taking an enema with 1 quart of warm RO filtered water or distilled water is very helpful do not retain this enema.
This procedure begins the cleansing of the colon, removing large particles of residue and most of the gas. When it is completed, the coffee retention enema may be taken. The warm water enema is optional and does not need to be taken if the coffee enema can be retained for the desired period. Place 1 quart of coffee in your enema bag or bucket.
You may use a Fleet enema bag, which is a disposable large volume plastic bag, an over-the-counter item from the local pharmacy or hospital supply outlet. This enema bag lasts about 2 years. The enema tip on the end of the hose is not adequate to give a "high enema. This colon tube is a soft flexible rubber-like tube around 30 inches in length. It follows the curves and flexure of the colon. The colon tube is usually inserted about 12 to 20 inches into the rectum.
It is difficult today to find a colon tube. However, a plastic rectal catheter or tube about 18 inches long may be ordered from your pharmacy as an over-the-counter item. The enema bag should not be over 36 inches higher than the rectum. If it is placed too high, the coffee runs into the colon too fast and under too much pressure, causing discomfort.
There are several positions that can be used while inserting the colon tube. There is also the knee-chest method, with chest and knees on the floor and buttocks in the highest position possible. Most people, however, find it easiest to lie on the left side until the solution is out of the bag or bucket. The enema should never be taken while sitting on the toilet or standing. Often, if a little bit of the solution is allowed to flow into the colon as the tube is being inserted, one may comfortably get past these kinks.
If a kink bends the tube too much and stops the flow of liquid, then the tube can be inserted only as far as it will go, still allowing the liquid to flow freely. Sometimes, if one hits a kink that stops the flow of the liquid completely, the tube can be pulled out slowly just to the point where the solution is felt flowing again. Frequently, the tube can be pushed back in, past the turn that previously stopped the liquid.
Regardless of the position used up to this point, one should now lie on the left side for at least 5 minutes, then on the back for another 5 minutes, then on the right side for at least 5 minutes.